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Influence of diuretics on brachial artery diameter and distensibility in hypertensive patients
Author(s) -
Laurent S.,
Lacolley PM,
Cuche JL,
Safar ME
Publication year - 1990
Publication title -
fundamental and clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 73
eISSN - 1472-8206
pISSN - 0767-3981
DOI - 10.1111/j.1472-8206.1990.tb00048.x
Subject(s) - brachial artery , medicine , blood pressure , diuretic , cardiology , pulse wave velocity , indapamide , radial artery , artery , pulse pressure , anesthesia
Summary— Blood pressure, brachial artery diameter and pulse wave velocity were determined before and after diuretic treatment in 2 groups of hypertensive patients treated either by indapamide (2.5 mg per d) or by canreonate (50 mg per d). Brachial artery diameter, measured from pulsed Doppler flowmetry, and pulse wave velocity, evaluated from mechanography, did not alter significantly despite a significant blood pressure reduction. The study indicates that, in hypertensive patients of middle age, diuretics did not change brachial artery diameter and distensibility, whether the drug caused an increase or a decrease in plasma potassium levels.