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Extensive dissemination of CTX‐M‐1‐ and CMY‐2‐producing Escherichia coli in poultry farms in Tunisia
Author(s) -
Mnif B.,
Ktari S.,
Rhimi F.M.,
Hammami A.
Publication year - 2012
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.2012.03309.x
Subject(s) - escherichia coli , biology , plasmid , cefotaxime , microbiology and biotechnology , enterobacteriaceae , poultry farming , gene , veterinary medicine , antibiotics , genetics , ecology , medicine
We characterized 67 Escherichia coli isolates with reduced susceptibility to cefotaxime obtained from 136 samples of healthy broilers housed in 36 Tunisian farms. All these isolates harboured bla CTX‐M‐1 and/or bla CMY‐2 genes located mostly on self‐conjugative IncI1 plasmids. qnrS1 , qnrA6 and aac(6′)‐Ib‐cr were detected in six isolates. Considerable genetic diversity was detected among isolates from different farms. To our knowledge, this is the first detailed documentation of a high occurrence of bla CTX‐M‐1 and bla CMY‐2 in E. coli at the poultry farm level in Tunisia as well as the first description of plasmid‐mediated quinolone resistance in food animals in Tunisia which may contribute to the dissemination of these genes throughout Tunisia.