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Phylogeography of Francisella tularensis ssp. holarctica in France
Author(s) -
Vogler A.J.,
Birdsell D.N.,
Lee J.,
Vaissaire J.,
Doujet C.L.,
Lapalus M.,
Wagner D.M.,
Keim P.
Publication year - 2011
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.2010.02977.x
Subject(s) - multiple loci vntr analysis , francisella tularensis , biology , phylogeography , biological dispersal , subclade , genotype , evolutionary biology , genetics , phylogenetics , zoology , genotyping , clade , virulence , demography , gene , population , sociology
Aim: To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates. Methods and Results: Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002‐00), and identified four major MLVA genotypes with no obvious geographical differentiation. Conclusions: The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two. Significance and Impact of the Study: This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.