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Virucidal efficacy of povidone‐iodine‐containing disinfectants
Author(s) -
Sauerbrei A.,
Wutzler P.
Publication year - 2010
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.2010.02871.x
Subject(s) - virology , microbiology and biotechnology , poliovirus , viral envelope , virus , biology
Aims: The objective of this study was to evaluate virucidal efficacy of the commercially available povidone‐iodine formulations Betaisodona ® solution and Betaseptic Mundipharma ® (Mundipharma). Methods and Results: The quantitative suspension test for virucidal testing of biocides according to the German guideline was used as method. The use of Betaisodona ® solution resulted in virucidal efficacy, corresponding to ≥10 4 ‐fold reduction in viral titre, against vaccinia virus, bovine viral diarrhoea virus and polyomavirus SV40 within 0·5 min and adenovirus type 5 within 3–5 min without and with organic load. For inactivation of the most resistant poliovirus type 1, a time interval of ≥60 min was needed. By contrast, Betaseptic Mundipharma ® inactivated significantly all model viruses for virucidal testing including poliovirus type 1 within 5 min independently from the addition of proteins. Conclusions: Betaisodona ® solution shows a good efficacy against enveloped model viruses as well as against some nonenveloped human viruses, e.g. adenovirus and polyomavirus. Betaseptic Mundipharma ® has an excellent virucidal efficacy including the inactivation of the most resistent poliovirus type 1. Significance and Impact of the Study: The findings of this study make Betaseptic Mundipharma ® suitable for virucidal disinfection of the skin within short time intervals.