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Propionibacterium acnes
Author(s) -
Perry A.L.,
Lambert P.A.
Publication year - 2006
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.2006.01866.x
Subject(s) - propionibacterium acnes , acne , sapho syndrome , pustulosis , palmoplantar pustulosis , osteitis , microbiology and biotechnology , medicine , dermatology , biology , immunology , osteomyelitis , psoriasis
Propionibacterium acnes , a common skin organism, is most notably recognized for its role in acne vulgaris. It also causes postoperative and device‐related infections and has been associated with a number of other conditions such as sarcoidosis and synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO), although its precise role as a causative agent remains to be determined. Propionibacterium acnes produces a number of virulence factors and is well known for its inflammatory and immunomodulatory properties. Recent publication of the P. acnes genome should provide further insights into the pathogenic capabilities of the organism and potentially lead to the development of new therapies.