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The effect of hypochlorite on spores of Bacillus subtilis lacking small acid‐soluble proteins
Author(s) -
Sabli M.Z.H.,
Setlow P.,
Waites W.M.
Publication year - 1996
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.1996.tb01190.x
Subject(s) - bacillus subtilis , library science , biology , computer science , bacteria , genetics
M.Z.H. SABLI, P. SETLOW AND W.M. WAITES. 1996. α/β‐Type small acid‐soluble proteins (SASP) bind to spore DNA and protect it against ultraviolet light, heat, hydrogen peroxide and freeze drying, making the spores much more resistant than vegetative cells to these agents. Spores of a mutant of Bacillus subtilis lacking the two major α/β‐type SASP were almost 30 000‐fold less resistant to hypochlorite than were wild‐type spores. After treatment with hypochlorite, surviving spores of the mutant, but not those of the wild type, showed higher levels of mutation, suggesting that SASP contribute to hypochlorite resistance by protecting spore DNA.