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Growth inhibition of a human oral bacterium Porphyromonas gingivalis by rat cysteine proteinase inhibitor cystatin S
Author(s) -
Umemoto T.,
Naito Y.,
Li M.,
Suzuki I.,
Namlkawa I.
Publication year - 1996
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.1996.tb00052.x
Subject(s) - porphyromonas gingivalis , microbiology and biotechnology , bacteria , proteinase inhibitor , cysteine , cystatin , cysteine proteinase inhibitors , bacteroidaceae , chemistry , biology , cystatin c , biochemistry , enzyme , renal function , genetics , programmed cell death , caspase , apoptosis
T. UMEMOTO, Y. NAITO, M. LI, I. SUZUKI AND I. NAMIKAWA. 1996. Agar diffusion analysis demonstrated that rat cystatin S, a cysteine proteinase inhibitor, inhibited the growth of all tested strains of a human oral, Gram‐negative anaerobic periodontopathogen Porphyromonas gingivalis. Its specific inhibitory activity against this tissue‐invasive bacterium but not against other tested oral bacterial species emphasized the importance of specific cysteine proteinases for growth of P. gingivalis.