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Antibacterial activity of flavanostilbenes against methicillin‐resistant Staphylococcus aureus
Author(s) -
Sato M.,
Tsuchiya H.,
Miyazaki T.,
Ohyama M.,
Tanaka T.,
Iinuma M.
Publication year - 1995
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.1995.tb01045.x
Subject(s) - staphylococcus aureus , microbiology and biotechnology , micrococcaceae , antibacterial agent , meticillin , methicillin resistant staphylococcus aureus , antibacterial activity , biology , antibiotics , bacteria , medicine , genetics
Three phytochemical compounds (alopecurone A‐C), flavanostilbenes which are produced by condensation between a hydroxyflavanone and a hydroxystilbene, were isolated as major components from the root of Sophora alopecuroides . They uniformly inhibited the growth of 21 strains of methicillin‐resistant Staphylococcus aureus with minimum inhibitory concentrations of 3·13–6·25 μg ml ‐1 .