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Progesterone transformation as a diagnostic feature in the classification of the Aspergillus niger group
Author(s) -
Mostafa M. Eman
Publication year - 1995
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.1995.tb00438.x
Subject(s) - aspergillus niger , biology , aspergillus , transformation (genetics) , biotransformation , hydroxyprogesterone , microbiology and biotechnology , fungi imperfecti , botany , biochemistry , enzyme , steroid , gene , hormone
Fifty‐five isolates of nine species and two species varieties (5 isolates each) of the Aspergillus niger group were tested for progesterone transformation. Generally, all isolates of the different species transformed progesterone to 21‐hydroxyprogesterone. In addition, the isolates of seven species have the capacity to hydroxylate progesterone to 11α‐hydroxyprogesterone. A systematic variation could be observed between the tested species of the Aspergillus niger group with respect to the transformation reactions of progesterone. Comparative biotransformation results showed that essential differences exist between the species of this group, where the different isolates of individual species always produce one or more identical products. This biochemical differentiation may supplement the morphological criteria used in the classification of this group of fungi.