Premium
Contamination of Indian maize with fumonisin B 1 and its effects on chicken macrophage
Author(s) -
Chatterjee D.,
Mukherjee S.K.
Publication year - 1994
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.1994.tb00861.x
Subject(s) - fumonisin b1 , fumonisin , phagocytosis , biology , fusarium , macrophage , immune system , population , microbiology and biotechnology , contamination , host (biology) , mycotoxin , in vitro , food science , immunology , botany , ecology , medicine , biochemistry , environmental health
The natural occurrence of fumonisin B 1 (FB 1 ) in Indian maize and its impact on the viability and phagocytosis of chicken peritoneal macrophages in vitro were investigated. FB 1 was found to be present at the levels of 300–366 ppm in Fusarium moniliforme ‐infected maize grains. The infected kernels in a population of 100 ears showed normal (Gaussian) frequency distribution. FB 1 , extracted from the contaminated kernels, reduced the viability and phagocytic activity of macrophages. These findings imply that FB 1 exposure may become a potential problem in India and may lead to decreased immune responses with consequent susceptibility of a host to infection.