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Cytotoxic effect of citrinin on relative division rate of Allium cepa root cells
Author(s) -
Sinha R.K.,
Dubey Anima,
Sinha K.K.
Publication year - 1992
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.1992.tb00663.x
Subject(s) - allium , library science , mathematics , humanities , biology , botany , art , computer science
Effect of different doses of citrinin, the secondary metabolite of Penicillium citrinum Thom, was investigated on Allium cepa root cells. A marked decrease in mitotic index was observed with the increased concentration of toxin. In controls the mitotic index was 16·2 which at a concentration of 400 ppb was reduced to the level of 4·7. Besides a decrease in mitotic index, several cytological abnormalities were also found, such as chromosome breakage, polyploidy, anaphase bridge, laggard, etc.