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Effect of chlorhexidine and phenoxyethanol on cell surface hydrophobicity of Gram‐positive and Gram‐negative bacteria
Author(s) -
Fitzgerald Karen A.,
Davies A.,
Russell A.D.
Publication year - 1992
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.1992.tb00656.x
Subject(s) - chlorhexidine , pseudomonas aeruginosa , escherichia coli , bacteria , microbiology and biotechnology , gram , gram negative bacteria , pseudomonadaceae , chemistry , mutant , biology , biochemistry , medicine , dentistry , genetics , gene
The surfaces of mutants of Escherichia coli and Pseudomonas aeruginosa were markedly more hydrophobic than the corresponding wild types, as were the latter when the organisms were pre‐treated with chlorhexidine diacetate (CHA) or phenoxyethanol (POE). A combination of CHA and POE demonstrated that only at higher concentrations was there a marked effect on hydrophobicity compared with that of either drug used alone. The three methods used to determine hydrophobicity correlated well as long as constant conditions were employed.