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Sensitivity and resistance of Escherichia coli and Staphylococcus aureus to chlorhexidine
Author(s) -
Fitzgerald Karen A.,
Davies A.,
Russell A.D.
Publication year - 1992
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/j.1472-765x.1992.tb00641.x
Subject(s) - welsh , resistance (ecology) , chlorhexidine , library science , microbiology and biotechnology , medicine , history , biology , archaeology , dentistry , ecology , computer science
Escherichia coli PC1349 and Staphylococcus aureus 6571 were sensitive to low concentrations of chlorhexidine diacetate, as determined by minimal inhibitory concentration tests. Lack of bactericidal response to 30 μ g/ml was due to the fact that adsorption of biocide to the cells was very slight in suspensions of high cell density and was not due to emerging resistance. Attempts by various methods to induce stable resistance in these organisms failed, despite reports that resistant strains have been isolated.