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phylochipanalyser — a program for analysing hierarchical probe sets
Author(s) -
METFIES KATJA,
BORSUTZKI PHILIPP,
GESCHER CHRISTINE,
MEDLIN LINDA K.,
FRICKENHAUS STEPHAN
Publication year - 2008
Publication title -
molecular ecology resources
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.96
H-Index - 136
eISSN - 1755-0998
pISSN - 1755-098X
DOI - 10.1111/j.1471-8286.2007.01927.x
Subject(s) - biology , hierarchy , robustness (evolution) , taxonomic rank , set (abstract data type) , consistency (knowledge bases) , identification (biology) , hierarchical clustering , data set , computational biology , data mining , artificial intelligence , computer science , ecology , cluster analysis , genetics , gene , economics , taxon , market economy , programming language
The recent introduction of phylochips that contain molecular probes facilitates environmental microbial identification in a single experiment without previous cultivation. A set of probes recognizing species at different taxonomic levels is denoted as a hierarchical set. Application of hierarchical probe sets on a DNA microarray allows the assessment of biodiversity with different resolutions. It significantly increases the robustness of the results retrieved from phylochip experiments because of the possible consistency checks of hybridization across different taxonomic levels. Here, we present a computer program, phylo‐chipanalyser , for the hierarchy editing and the evaluation of phylochip data generated from hierarchical probe sets.