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Common molecular mechanisms in explicit and implicit memory
Author(s) -
Barco Angel,
Bailey Craig H.,
Kandel Eric R.
Publication year - 2006
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.2006.03870.x
Subject(s) - neuroscience , hippocampus , aplysia , mechanism (biology) , focus (optics) , computer science , explicit memory , memory formation , cognitive science , biology , cognitive psychology , episodic memory , psychology , cognition , physics , quantum mechanics , optics
Cellular and molecular studies of both implicit and explicit memory suggest that experience‐dependent modulation of synaptic strength and structure is a fundamental mechanism by which these memories are encoded and stored within the brain. In this review, we focus on recent advances in our understanding of two types of memory storage: (i) sensitization in Aplysia , a simple form of implicit memory, and (ii) formation of explicit spatial memories in the mouse hippocampus. These two processes share common molecular mechanisms that have been highly conserved through evolution.