Premium
Neurochemistry of GABAergic System in Cerebral Cortex Chronically Exposed to Bromide In Vivo
Author(s) -
Balcar Vladimir J.,
Erdö Sandor L.,
Joó Ferenc,
Kása Péter,
Wolff Joachim R.
Publication year - 1987
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1987.tb13142.x
Subject(s) - neurochemical , gabaergic , cerebral cortex , bromide , in vivo , neurochemistry , chemistry , neuroscience , cortex (anatomy) , inhibitory postsynaptic potential , endocrinology , medicine , biology , organic chemistry , microbiology and biotechnology , neurology
Neurochemical correlates of GABAergic synaptic transmission [binding, uptake, metabolism, and tissue content of γ‐aminobutyric acid (GABA)] were investigated in the cortex of rats that had been given 27 m M bromide in drinking water for periods of time ranging from 1 day to 1 month. No effect of bromide on any of the parameters was found and it is concluded that chronic administration of bromide has no profound effect on GABAergic inhibitory system in the rat cortex.