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Sialosyllactotetraosylceramide, 3′‐isoLM1, a Ganglioside of the Lactotetraose Series Isolated from Normal Human Infant Brain
Author(s) -
Molin Kent,
Mansson JanEric,
Fredman Pam,
Svennerholm Lars
Publication year - 1987
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1987.tb03417.x
Subject(s) - ganglioside , antigen , monoclonal antibody , human brain , antibody , chemistry , biochemistry , biology , immunology , neuroscience
A ganglioside antigen was detected in infant human brains by the monoclonal antibody C‐50. Structural analysis of the isolated ganglioside antigen showed it to be 3′‐isoLM1, Sialosyllactotetraosylceramide. The concentration of this ganglioside in human infant brain was 0.5 nmol/g.