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Neuronal and Nonneuronal Contributions to Renal Catecholamine Content in the Dog
Author(s) -
Petrovic T.,
Anderson W. P.,
Bell C.
Publication year - 1986
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1986.tb04518.x
Subject(s) - catecholamine , denervation , dopamine , medulla , medicine , endocrinology , kidney , cortex (anatomy) , adrenal medulla , population , renal medulla , renal cortex , chemistry , biology , neuroscience , environmental health
Endogenous noradrenaline and 3,4‐dihydroxyphenylethylamine (dopamine) levels were measured in different zones of the dog kidney following chronic unilateral renal denervation. In outer and inner renal cortex, and in outer medulla, >95% of the tissue content of both catecholamines was contributed by renal nerves, whereas in inner medulla only nonneuronal catecholamines were found. The amounts of neuronal dopamine present in outer renal cortex were greater than would be expected for a population of solely noradrenergic nerves.