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Comparison of Benzodiazepine Receptors in Cerebellum and Inferior Colliculus
Author(s) -
Sieghart W.
Publication year - 1986
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1986.tb00698.x
Subject(s) - inferior colliculus , cerebellum , gabaa receptor , neuroscience , receptor , superior colliculus , benzodiazepine , biology , nucleus , biochemistry
Reversible and irreversible binding of [ 3 H]flunitrazepam was investigated in membranes from cerebellum and inferior colliculus of young and adult rats. Results indicate that in adult animals predominantly BZ 1 receptors are enriched in both brain regions. In the brains of newborn animals, however, additional benzodiazepine receptor subtypes seem to exist in cerebellum as well as in inferior colliculus.