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Glutamyl‐Taurine Is the Predominant Synaptic Taurine Peptide
Author(s) -
Marnela KirsiMarja,
Morris Howard R.,
Panico Maria,
Timonen Maritta,
Lähdesmäki Pekka
Publication year - 1985
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1985.tb12878.x
Subject(s) - taurine , fast atom bombardment , chemistry , peptide , serine , biochemistry , synaptic vesicle , amino acid , mass spectrometry , vesicle , chromatography , enzyme , membrane
Several taurine‐containing peptides have been identified from trichloracetic acid extracts of synaptosomes and their subcellular vesicles prepared from calf brain. These peptides contain aspartic and glutamic acids, serine and taurine, and are often present in an N ‐acetylated form. The peptides were isolated as single spots by TLC. Glutamyl‐taurine was found to be the predominant structure when analyzed by fast atom bombardment (FAB) mass spectrometry.