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Expression of Hyaluronectin by C‐6 Glial Cells at High Density
Author(s) -
Bhat Narayan R.,
Brunngraber Eric G.,
Delpech Bertrand
Publication year - 1985
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1985.tb07174.x
Subject(s) - glial fibrillary acidic protein , immunoperoxidase , gfap stain , neuroglia , glutamine synthetase , glycoprotein , biology , astrocyte , microbiology and biotechnology , chemistry , biochemistry , immunohistochemistry , glutamine , central nervous system , antibody , monoclonal antibody , neuroscience , immunology , amino acid
Hyaluronectin, a brain glycoprotein that has been localized to the nodes of Ranvier in vivo and to oligodendrocytes in primary cultures of neonatal rat brain cells, was shown by using an unlabeled immunoperoxidase method to be present in C‐6 glial cells grown to high density. The density‐dependent expression of this glycoprotein is in accordance with the known properties of the glial stem cells, i.e., induction of differentiated properties such as 2′,3′‐cyclic nucleotide‐3′‐phosphohydrolase, glutamine synthetase, S‐100 protein, and glial fibrillary acidic protein.