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Cholesterol Esters in Rat Brain Infected with Acute Measles Encephalitis: Concentration and Fatty Acid Composition
Author(s) -
Abe Toshiaki,
Ogawa Kiyoko,
Hiraiwa Mikio,
Kobune Fumio,
Nagashima Kazuo
Publication year - 1983
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1983.tb11841.x
Subject(s) - cholesterol , cerebrum , encephalitis , measles , chemistry , measles virus , fatty acid , composition (language) , virus , inoculation , biochemistry , biology , virology , central nervous system , endocrinology , immunology , vaccination , linguistics , philosophy
The present study deals with the concentration and fatty acid composition of cholesterol esters in rat brains infected experimentally with measles virus to induce acute encephalitis. The left side of the cerebrum, as well as other portions of the brain, when inoculated per‐cutaneously contained a large amount of cholesterol esters. The major fatty acids from the esters in the brain were C 16:0 , C 16:1 , C 18:0 , and C 18:1 ; those from the serum were C 18:1 , C 18:2 , and C 20:4 This result indicates that cholesterol esters may not come from serum but can be synthesized in situ , even in the brain with acute viral infection.