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Effect of Maternal Iron Deficiency in Rat on Serotonin Uptake In Vitro by Brain Synaptic Vesicles in the Offspring
Author(s) -
Kaladhar M.,
Rao B. S. Narasinga
Publication year - 1983
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1983.tb08155.x
Subject(s) - offspring , serotonin , synaptic vesicle , vesicle , endocrinology , medicine , iron deficiency , in vitro , biology , chemistry , pregnancy , biochemistry , receptor , anemia , genetics , membrane
The effect of maternal dietary iron deficiency on brain synaptic vesicle [ 3 H]serotonin (5‐HT) uptake and iron content in the offspring was examined in rats. Pups born to iron‐deficient mothers revealed significant deficits in vesicular [ 3 H]5‐HT uptake and iron concentration at 21 days of age. These changes were, however, found to be reversible with postweaning iron repletion.