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Changes in Monoamine Oxidase Activity in Rat Brain During Alloxan Diabetes
Author(s) -
Mayanil C. S. K.,
Kazmi S. M. I.,
Baquer N. Z.
Publication year - 1982
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1982.tb10869.x
Subject(s) - monoamine oxidase , alloxan , diabetes mellitus , endocrinology , monoamine neurotransmitter , medicine , chemistry , neuroscience , pharmacology , biology , biochemistry , serotonin , enzyme , receptor
The effect of alloxan diabetes on the activity of monoamine oxidase was studied in three regions of the rat brain at various time intervals after the onset of diabetes. It was observed that monoamine oxidase activity was decreased at early time intervals after diabetes, followed by a recovery in all three regions of the brain. A reversal of the effect was observed with insulin administration to the diabetic rats.