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The Effect of Visual Deprivation on β‐Adrenergic Receptors in the Visual Centres of the Rat Brain
Author(s) -
Schliebs Reinhard,
Burgoyne Robert D.,
Bigl Volker
Publication year - 1982
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1982.tb05345.x
Subject(s) - dihydroalprenolol , receptor , adrenergic receptor , endocrinology , medicine , visual cortex , sensory deprivation , geniculate , lateral geniculate nucleus , neuroscience , geniculate body , chemistry , biology , nucleus , sensory system , antagonist , partial agonist
The levels of binding of [ 3 H]dihydroalprenolol to β‐adrenergic receptors in the visual centres and frontal cortex from brains of control, dark‐reared and monocularly deprived rats were compared. Receptor binding is changed in monocularly deprived rats in the lateral geniculate nuclei and superior colliculi of both sides. Scatchard analyses indicated that the changes in the [ 3 H]dihydroalprenolol binding in the lateral geniculate nuclei were due to alterations in both receptor affinity and receptor number. No effect of dark‐rearing could be detected.