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Acyl‐CoA: sn‐Glycerol‐3‐Phosphate O‐Acyltransferase in Rat Brain Mitochondria and Microsomes
Author(s) -
Fitzpatrick Susan M.,
Sorresso Giovanna,
Haldar Dipak
Publication year - 1982
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1982.tb04738.x
Subject(s) - microsome , acyltransferase , mitochondrion , biochemistry , acylation , acyltransferases , chemistry , acyl coa , enzyme , biosynthesis , catalysis
The subcellular distribution of acyl‐CoA: sn ‐glycerol‐3‐phosphate O‐acyltransferase between brain mitochondria and microsomes was investigated. The activities associated with purified rat brain mitochondrial and microsomal preparations could be distinguished by differences in their acyl‐CoA specificity, products of acylation, and sensitivity to N ‐ethylmaleimide, trypsin, acetone, and polymyxin B. It was concluded that both brain mitochondria and microsomes possess the acyltransferase.