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No Evidence for Lateral Asymmetry of Neurotransmitters in Post‐Mortem Human Brain
Author(s) -
Rossor M.,
Garrett N.,
Iversen L.
Publication year - 1980
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1980.tb03716.x
Subject(s) - human brain , laterality , choline acetyltransferase , dopamine , glutamate decarboxylase , neuroscience , neurotransmitter , brain asymmetry , biology , endocrinology , medicine , lateralization of brain function , psychology , central nervous system , biochemistry , enzyme
: A study of post‐mortem human brain was undertaken to establish whether there is any evidence for lateral asymmetry of neurotransmitters. Choline acetyltransferase, glutamic acid decarboxylase, α‐aminobutyric acid, dopamine and noradrenaline were measured in nine comparable areas from the left and right hemispheres of normal post‐mortem human brain. Only nigral GABA showed a left‐right difference at a significance level of 5%. These negative post‐mortem findings suggest that chemical laterality is unlikely to be an important source of error in human post‐mortem studies.