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α‐Guanidinoglutaric Acid in Cobalt‐Induced Epileptogenic Cerebral Cortex of Cats
Author(s) -
Mori Akitane,
Akagi Masayuki,
Katayama Yasuto,
Watanabe Yoko
Publication year - 1980
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1980.tb03697.x
Subject(s) - cats , cerebral cortex , neuroscience , cobalt , chemistry , psychology , medicine , inorganic chemistry
: Guanidino compounds in the cobalt‐induced epileptogenic cerebral cortex of cats were fluorometrically analysed by a JASCO G‐520 guanidino compounds analyser, and an unknown high peak was observed in the chromatogram that was identical to the peak of authentic α‐guanidinoglutaric acid. In another experiment, the substance was extracted from the cobalt focus tissue, converted into dimethylpyrimidyl derivative‐butylester, and analysed by a GC/MS technique. The mass spectrum of the substance was identical to the dimethylpyrimidyl derivative of α‐guanidinoglutaric acid butylester (M + = 365).