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A CALCIUM ACTIVATED PROTEASE IN SQUID AXOPLASM
Author(s) -
PANT Harish C.,
Terakawa Susumu,
Gainer Harold
Publication year - 1979
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1979.tb04515.x
Subject(s) - axoplasm , squid , protease , biochemistry , neutral protease , neurofilament , biophysics , chemistry , calcium , microbiology and biotechnology , biology , enzyme , immunology , immunohistochemistry , ecology , organic chemistry , axon
Evidence for a protease in squid axoplasm which is selectively activated by Ca 2+ and blocked by SH‐inhibitors is presented. This protease appears to be particularly effective in degrading squid neurofilament proteins, but also extensively degrades various other major protein components in axoplasm.