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PEROXIDATION OF RAT BRAIN MITOCHONDRIAL LIPIDS 1
Author(s) -
Sharma O. P.
Publication year - 1977
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1977.tb12335.x
Subject(s) - lipid peroxidation , mitochondrion , phosphatidylcholine , chemistry , biochemistry , peroxide , lipid peroxide , phospholipid , oxidative stress , membrane , organic chemistry
— Phospholipids, particularly phosphatidylcholine, are the main substrates for lipid peroxidation in rat brain mitochondria. The neutral lipids do not undergo peroxidation. The lipoproteins of mitochondria in their native form protect the phospholipids from auto‐oxidation. The mitochondrial protein fraction stimulates peroxide formation presumably due to its surface active properties.