Premium
A MASS FRAGMENTOGRAPHIC ASSAY OF 3‐METHOXYTYRAMINE IN RAT BRAIN
Author(s) -
Galli C. L.,
Cattabeni F.,
Eros T.,
Spano P. F.,
Algeri S.,
Giulio A. Di,
Groppetti A.
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb10410.x
Subject(s) - metabolite , dopaminergic , chemistry , dopamine , chromatography , biochemistry , endocrinology , medicine
— A mass fragmentographic method for the measurement of 3‐methoxytyramine, a metabolite of dopamine formed after its neuronal release, is described. This method allows the assay of this dopamine metabolite in the picogram range, thus utilizing only few milligrams of brain areas containing dopaminergic neurons. Moreover, the method is simple and possesses the high specificity intrinsic to mass fragmentography.