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BRAIN‐SPECIFIC ANTIGENS IN THE QUAKING MOUSE DURING ONTOGENY
Author(s) -
Jacque C. M.,
Jørgensen O. S.,
Baumann Nicole A.,
Bock Elisabeth
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb05153.x
Subject(s) - antigen , glial fibrillary acidic protein , biology , ontogeny , immunoelectrophoresis , mutant , cytoplasm , membrane protein , microbiology and biotechnology , biochemistry , immunology , membrane , endocrinology , immunohistochemistry , gene
— By means of crossed Immunoelectrophoresis the concentrations of 7 brain‐specific antigens have been investigated during the ontogenic development of normal and Quaking mice. Two proteins, the glial fibrillary acidic protein and the brain‐specific membrane protein D5 were found to be strongly increased in mutant brains. The synaptosomal antigen synaptin (Cl), the 14‐3‐2 protein of neuronal cytoplasm, and the neuronal membrane antigens D1, D2 and D3 were all present at normal levels in mutant brains.