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THE FORMATION OF PEPTIDO‐AMINES FROM CONSTITUENT AMINO ACIDS AND HISTAMINE IN HYPOTHALAMIC TISSUE
Author(s) -
Reichelt K. L.,
Edminson P. D.,
Kvamme E.
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb04455.x-i1
Subject(s) - histamine , incubation , sephadex , clearance , amino acid , chemistry , chromatography , biochemistry , biology , endocrinology , enzyme , medicine , urology
—The formation of peptido‐amines from acetylaspartic acid and histamine incubated with amino acids Glu, Gly, Ser, Ala and GABA is described. The incubation was performed using a 16000 g × 30 min supernatant extract of hypothalamic tissue which had been cleared of small molecular weight compounds by passage through a G‐25 Sephadex column.