Premium
MONOAMINES AS POSSIBLE MEDIATORS IN THE REGULATION OF FAST AXOPLASMIC FLOW
Author(s) -
Boegman R. J.,
Wood P. L.
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb04445.x-i1
Subject(s) - monoaminergic , monoamine neurotransmitter , chemistry , axoplasmic transport , spinal cord , sciatic nerve , neuroscience , biophysics , biology , anatomy , biochemistry , serotonin , receptor
—The effect of drugs which have been shown to alter monoamines in the CNS on the rate of fast axoplasmic flow of [ 3 H]leucine labelled material in the rat sciatic nerve was examined. Drugs which deplete monoamines led to a decrease while those which increase the level of monoamines led to an increase in the rate of fast axoplasmic flow. Monoaminergic drugs were also found to alter the amount of [ 3 H]leucine incorporated into spinal cord.