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OCCURRENCE AND FORMATION OF γ‐GLUTAMYLPUTRESCINE IN MAMMALIAN BRAIN
Author(s) -
Nakajima T.,
Kakimoto Y.,
Tsuji M.,
Konishi H.
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb04444.x
Subject(s) - putrescine , myelin , trichloroacetic acid , chemistry , biochemistry , isolation (microbiology) , central nervous system , chromatography , biology , neuroscience , enzyme , microbiology and biotechnology
Abstract —An unknown radioactive compound was detected in the basic fraction of the trichloroacetic acid extract of rat brain injected with radioactive putrescine. This compound was purified from bovine brain and identified as γ‐glutamylputrescine by comparison of its behaviour with that of the synthesized glutamylamides. The amide seemed to be metabolized as rapidly as putrescine in rat brain.