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THE EFFECT OF HYPOXIA ON THE PENTOSE PHOSPHATE PATHWAY IN BRAIN
Author(s) -
Hakim A. M.,
Moss G.,
Gollomp S. M.
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb04436.x-i1
Subject(s) - pentose phosphate pathway , pentose , in vivo , hypoxia (environmental) , metabolism , labelling , biochemistry , in vitro , carbohydrate metabolism , chemistry , glycolysis , metabolic pathway , phosphate , biology , oxygen , genetics , organic chemistry , fermentation
—The role of the pentose phosphate pathway in brain glucose metabolism was studied in hypoxic rats. The method of directly labelling the 6‐phosphogluconate pool was used in both in vivo and in vitro experiments. Results indicate that there is significantly more glucose metabolized via this pathway in brains of hypoxic rats than in the controls.