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CELLS ISOLATED FROM TRYPSIN‐TREATED BRAIN CONTAIN TRYPSIN
Author(s) -
Guarnieri M.,
Cohen S. R.,
Ginns E.
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb04433.x
Subject(s) - trypsinization , trypsin , enzyme , biochemistry , cell , chemistry , microbiology and biotechnology , biology
—Neuronal and oligodendroglial cell fractions isolated from trypsinized brain contain trypsin. Neuronal cell bodies contained approximately 5 μ g of trypsin/mg of cell protein; oligodendroglial cells had approx 1 μ g of enzyme activity. Studies with fluorescein‐conjugated trypsin suggested that least a portion of the fluorescent enzyme was internalized in neurons.