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7S NERVE GROWTH FACTOR PROTEIN IN THE GOLDEN HAMSTER
Author(s) -
Shine H. D.,
PerezPolo J. R.
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb02609.x
Subject(s) - nerve growth factor , hamster , golden hamster , growth factor , biology , anatomy , microbiology and biotechnology , chemistry , biochemistry , receptor
– Levels of 7S nerve growth factor in various tissues of the Golden Hamster were measured using a new assay procedure. The assay consisted of labelling native 7S nerve growth factor by allowing an 125 I‐labelled subunit ([ 125 I]‐α) of 7S nerve growth factor to compete with the native a subunit. The presence of 7S nerve growth factor was noted in a wide variety of non‐neuronal and neuronal tissues. Levels of 7S nerve growth factor in the CNS decreased as the distance from the metencephalon increased both rostrally and caudally.