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EFFECT OF UNILATERAL VISUAL DEPRIVATION AND VISUAL STIMULATION ON THE ACTIVITIES OF GLUTAMATE DECARBOXYLASE, GABA‐α KETOGLUTARATE TRANSAMINASE, ASPARTATE AMINOTRANSFERASE AND HEXOKINASE OF THE OPTIC LOBE OF THE ADULT PIGEON
Author(s) -
Chakrabarti T.,
Daginawala H. F.
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb01575.x
Subject(s) - enucleation , stimulation , endocrinology , glutamate receptor , transaminase , medicine , glutamate decarboxylase , sensory deprivation , gaba transaminase , biology , biochemistry , neuroscience , enzyme , sensory system , genetics , receptor
— A study was made of the effect of unilateral visual deprivation and stimulation upon the activities of glutamate decarboxylase (EC 4.1.1.15), GABA‐α‐ketoglutarate transaminase (EC 2.6.1.19). aspartate aminotransferase (EC 2.6.1.1) and hexokinase (EC 2.7.1.1) in the optic lobe of the adult pigeon ( Columba Livia ). Visual deprivation was achieved by eyelid suturing or by enucleation and maintained for 1–9 weeks. Unilateral visual stimulation was maintained for 75 min following 72 h in the dark. A small but significant increase was observed in the activities of glutamate decarboxylase and aspartate aminotransferase after unilateral visual stimulation and a decrease after unilateral enucleation. The activities of GABA‐α‐ketoglutarate transaminase and hexokinase decreased after unilateral visual stimulation and increased after enucleation. Unilateral eyelid suturing resulted in a significant reduction in the activity of glutamate decarboxylase and an increase in the activity of GABA‐α‐ketoglu‐tarate transaminase. Hexokinase activity was, however, unchanged following unilateral eyelid suturing.