Premium
ALTERATIONS IN ACETYLCHOLINESTERASE ISOENZYME PATTERN OF HIPPOCAMPUS AFTER SEPTAL LESIONS IN RAT BRAIN
Author(s) -
OderfeldNowak Barbara,
SkangielKramska Jolanta
Publication year - 1976
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1976.tb00334.x
Subject(s) - acetylcholinesterase , hippocampus , aché , isozyme , enzyme , polyacrylamide gel electrophoresis , biology , biochemistry , anatomy , microbiology and biotechnology , endocrinology , chemistry
— The effect of septal lesions upon the AChE (EC 3.1.1.7) isoenzymic pattern in the hippocampus of the rat brain was studied 1–3 months after surgery by means of polyacrylamide disc electrophoresis. Alterations in the isoenzymic pattern were found in the membrane‐bound but not in the soluble fraction of the enzyme. In addition to the two slowly migrating bands seen in the membrane‐bound AChE fraction of the normal hippocampus, the fast‐migrating isoenzyme becomes visible.