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EFFECT OF DELTA‐9‐TETRAHYDROCANNABINOL ADMINISTRATION ON THE LIPID CONSTITUENTS OF RAT BRAIN SUBCELLULAR FRACTIONS
Author(s) -
Sarkar C.,
Ghosh J. J.
Publication year - 1975
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1975.tb11891.x
Subject(s) - cerebroside , phospholipid , myelin , microsome , chemistry , pharmacology , lipid metabolism , intraperitoneal injection , medicine , biochemistry , endocrinology , central nervous system , biology , enzyme , membrane
Abstract— An investigation on the effects of acute (10 mg/kg) and chronic (10 mg/kg for 15 days) treatment with Δ 9 ‐THC administration by the intraperitoneal route, on the cholesterol, cerebroside and individual phospholipid contents in microsomal, synaptosomal, mitochodrial and myelin fractions from adult rat brain, is reported. The drug has been found to affect the different subcellular membranous lipid and phospholipid components in a characteristic manner.