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THE VISUALIZATION OF CONCANAVALIN‐A BINDING SITES IN THE INTERPERIOD LINE OF RAT SCIATIC NERVE MYELIN
Author(s) -
Wood J. G.,
McLaughlin Barbara J.
Publication year - 1975
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1975.tb11870.x
Subject(s) - sciatic nerve , concanavalin a , myelin , lectin , glycoprotein , chemistry , myelin associated glycoprotein , myelin sheath , axoplasmic transport , biochemistry , neuroscience , microbiology and biotechnology , biology , anatomy , central nervous system , in vitro
— The plant lectin, Concanavalin A (Con A), is used in combination with a peroxidase‐labelling technique to visualize carbohydrates in myelin. The major myelin glycoprotein seen by polyacrylamide electophoresis binds Con A. Thin slices of sciatic nerve bind Con A in the interperiod line of the myelin. These data suggest that the glycoprotein may be located at the interperiod line.