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THE STIMULATION OF ARGININE PHOSPHOKINASE IN LOBSTER AXONS BY GABA
Author(s) -
Maki Y.,
Cooper J. R.
Publication year - 1975
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1975.tb07672.x
Subject(s) - arginine , arginine kinase , stimulation , chemistry , phosphate , neuroscience , medicine , endocrinology , biology , biochemistry , amino acid
— GABA at physiological concentrations has been shown to stimulate the synthesis of arginine phosphate in lobster walking nerves. This effect can be observed both in intact axons and in axonal homogenates. The stimulatory activity of GABA on the synthesis of arginine phosphate appears to be on the V max of arginine phosphokinase whereas in the reverse reaction the effect is referable to the K m of ADP.