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CHANGES IN THE ACETYLCHOLINE CONTENT OF DIFFERENT BRAIN REGIONS OF THE RAT DURING A LEARNING EXPERIMENT 1
Author(s) -
Matthies H.,
Rauca Ch.,
Liebmann H.
Publication year - 1974
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1974.tb12206.x
Subject(s) - acetylcholine , striatum , hippocampus , hippocampal formation , neuroscience , visual cortex , cortex (anatomy) , cerebral cortex , chemistry , psychology , endocrinology , biology , dopamine
— The ACh content of the rat hippocampus, visual cortex, auditory cortex and corpus striatum was estimated as so‐called free, labile‐bound and stable bound acetylcholine at different times after the learning of a brightness discrimination. In the hippocampal region the free acetylcholine was highly increased immediately after the training, whereas the stable bound ACh and the labile‐bound fraction rose 70 min and 4 h respectively‐after completion of training. Only small alterations of the ACh fractions were observed in the visual and auditory cortices. In the corpus striatum no changes appeared.