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NUCLEAR PROTEINS IN BRAIN OF 7‐DAY‐OLD AND ADULT RATS
Author(s) -
Szijan I.,
Burdman J. A.
Publication year - 1973
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1973.tb07563.x
Subject(s) - biology , leucine , histone , brain development , nuclear protein , endocrinology , medicine , biochemistry , neuroscience , amino acid , transcription factor , gene
— The incorporation of radioactive leucine into proteins of rat brain was considerably higher in the 7‐day‐old than in the adult rat. The greatest difference in the rate of protein synthesis between these two stages of development occurs in the mitochondrial fraction. Among the nuclear proteins the largest variation was in the histones. The only difference in the relative content of nuclear proteins between 7‐day‐old and adult brain was in the acidic deoxyribonucleoproteins which was higher in the younger animal. The electrophoretic profile of these proteins changed during brain development.