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CATION UPTAKE BY INTACT NUCLEI FROM RAT CEREBRAL CORTEX
Author(s) -
Haljamäe H.,
Waldman A. A.
Publication year - 1973
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1973.tb00289.x
Subject(s) - divalent , potassium , magnesium , chemistry , biophysics , sodium , manganese , cerebral cortex , calcium , cortex (anatomy) , cationic polymerization , biochemistry , biology , neuroscience , organic chemistry
A method is described for determining the uptake of cations by intact nuclei from rat cerebral cortex. The divalent cations of magnesium, manganese and calcium were found to be concentrated in the nuclear pellet to levels well above the initial concentration of the medium, whereas little uptake of either potassium or sodium was observed. The binding of divalent cations to the nuclei will produce a cationic environment quite different from that of the external medium. Such localized differences may play a role in the control of nuclear activities.