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Desmosterol levels in human foetal brain—a reassessment
Author(s) -
Dennick R. G.,
Dean P. D. G.,
Abramovich D. A.
Publication year - 1973
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1973.tb00102.x
Subject(s) - desmosterol , central nervous system , myelin , neuroscience , myelin sheath , human brain , brain development , brain tissue , chemistry , biology , endocrinology , cholesterol , sterol
C holesterol , an essential component of the central myelin sheath, is synthesized in large quantities during myelination in the central nervous system. However, in rat brain prior to and during the early stages of myelination desmosterol accumulates in significant amounts (F umagalli and P aoletti , 1963; K ritchevsky and H olmes , 1962)