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RAPIDLY REASSOCIATING DNA OF RAT BRAIN
Author(s) -
Ranjekar P. K.,
Murthy M. R. V.
Publication year - 1973
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1973.tb00094.x
Subject(s) - dna , denaturation (fissile materials) , biology , population , base pair , microbiology and biotechnology , biochemistry , chemistry , medicine , environmental health , nuclear chemistry
— DNA's were isolated from brains of rats at different stages of growth and were fractionated on hydroxyapatite columns on the basis of their denaturation and reassociation properties. The results indicate that rat brain DNA had a heterogeneous population of base sequences. Approximately 10 per cent of the total DNA exhibited rates of reassociation characteristic of repetitive DNA. Differences were also observed in the pattern of denaturation of brain and liver DNA's of newborn and adult rats.