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PARTIAL CHARACTERIZATION OF A NEW MYELIN PROTEIN COMPONENT
Author(s) -
Agrawal H. C.,
Burton R. M.,
Fishman M. A.,
Mitchell R. F.,
Prensky A. L.
Publication year - 1972
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1972.tb05118.x
Subject(s) - myelin , white matter , polyacrylamide gel electrophoresis , myelin basic protein , myelin sheath , isolation (microbiology) , chemistry , gel electrophoresis , biochemistry , microbiology and biotechnology , biology , chromatography , central nervous system , enzyme , neuroscience , medicine , magnetic resonance imaging , radiology
A new protein component has been demonstrated in myelin isolated from rat whole brain and from white matter dissected from bovine, dog and rabbit brain. It is also present in rabbit optic nerve. It does not appear to be present in other subcellular fractions of rat brain. It has a molecular weight of 20,540 ± 490(S.D.), as determined by polyacrylamide gel electrophoresis in sodium dodecyl sulphate. A rapid procedure for the isolation of myelin is also described.