Premium
THE PERMEABILITY OF PINCHED‐OFF NERVE ENDINGS TO SODIUM, POTASSIUM AND CHLORIDE AND THE EFFECTS OF GRAMICIDIN
Author(s) -
Keen P.,
White T. D.
Publication year - 1971
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1971.tb12038.x
Subject(s) - gramicidin , potassium , chemistry , permeability (electromagnetism) , sodium , ion , choline , biophysics , chloride , free nerve ending , analytical chemistry (journal) , inorganic chemistry , chromatography , membrane , biochemistry , anatomy , organic chemistry , biology
—1 The passive permeability of synaptosomes to ions was measured by a light‐scattering technique. Synaptosomes were freely permeable to acetate, HCO 3 _ , SCN − and NH 4 + and were impermeable to choline and SO 4 2‐ . 2 Gramicidin D selectively increased the permeability of synaptosomes to Na + and K + ions. 3 The relative permeabilities of Na + , K + and Cl − , measured in the presence of a number of more permeant counter‐ions, was in the ratio 1:19:12. These values are discussed in terms of the source of the resting potential.